back after new year!

Hey all! Hope people still are checking back. I think that after the new year i'm gonna be doing some videos on youtube, which i'll post here. Anyway, hope everyone having a lovely holiday, christmas and have a good new year!

These new pictures are from my new camera. 25 years 2 months old in these. Other photos with my webcam

Skin Care, Supplements, Exercise

Not that much difference, really unsure about going into a serious anti aging skin care regimen right now at my age. =/ So looked for more on the side of prevention than anything else.

Skin care

- Neutrogena gentle exfoliating face wash
- Skinceuticals CE ferulic acid
- Derma + intensive base with CoQ10, gingko biloba, vitamin A and Vitamin E
- Derma + night cream with macadamia oil, CoQ10, vitamin E, (also a slightly different day time one without mac..)
Derma + intensive eye cream CoQ10, vitamin E, retinyl palmitate, jojaba oil.
- Sun screen (mostly just in the summer)
- Apply white tea / green tea to the skin
- Aloe vera gel day time.
- Avoiding long exposure to the sun :-D

Supplements;

- Reflex Instant Whey Protein - twice a day 2x25g http://www.reflex-nutrition.com/faqs.php?faq=whey_protein

- Vitamin C (ascorbic acid) 2000mg

- Essential mix 1/3 of the dose http://www.aor.ca/html/products.php?id=57

- Carnosine 500 - http://www.aor.ca/html/products.php?id=40

- Vitamin D3 5000IU (5000IU all year because I don't go in the sun much) http://www.aoreurope.co.uk/product/view/3017

- Fish oil / cod liver oil, seven seas - http://www.codliveroil.co.uk/productRange/histrength/xtrahsclo.htm

- Magnesium Oxide 300mg

- Zinc 15mg

- AOR Biotics (many different types of probiotics)

- Lactoferrin 1 x 250mg (I also get 500mg of lactoferrin from whey protein)

- AOR Green tea (EGCG) x 1 Capsule a day

- AHCC

- Rowse Manuka honey - Prevents throat infections, kills bugs like strep, staph, h pylori.
http://www.rowsehoney.co.uk/articles/honey-and-you/manuka-honey-science

- Cranberry

Exercise.

- Running (30 minutes a day) - not for fun, but makes me feel good anyway.
- Ashtanga Yoga 4 days a week 1 hour a day - maintain flexibility and strength
- Free weights twice a week, bench press, squats etc etc... to mostly maintain muscle mass and -decrease risk of osteoporosis because of low body weight.

Hola a todos!

I hope everyone is still out there and checking back to my blog every now and then. I am sorry for the lack of updates over the last couple of months. I can make up many excuses but the truth is that I had nothing really good to write about in a while so I thought that I'd rather not ramble on about anything on my blog all the time. Which is not good when what readers are after is good information and news. However as my first post back from my quiet period, I will just say what I've been upto since I lasted posted.

So a while ago I started to learn to speak spanish, and I have been studying a lot, in the first 2 months I actually studied for 4-6 hours daily! I met two wonderful people, Mariangel, and Tere who both are great, they come from venezuela and it's been fun talking to them both. Actually I even plan to go to venezuela for sometime in 2010 in the summer! Now I'm definitely going to need a lot of sunblock if I want to keep my youhtful looks while I am there! The other thing is that next year I also want to move to spain, most likely will be Madrid... I don't know for how long but it's something I have to do, I'm 25 on the 21st of this month and I feel I have to just do something now, not be locked into the same boring stuff day in and day out. Meet new people, see new things, go on and adventure. Actually, I love adventures, so I'm quite excited about this. I am going to book a plane ticket and my friend jamie will go with me, also another friend craig is planning on going to spain for a year or so also, I have yet to talk with him more about this but it could be really good. I will obviously continue to do my CR while I am there, and while I go to venezuela. I worry a bit about the safety of me being in venezuela though because apparently it's not exactly the safest place one can go to from what I was told by mariangel.

Over the last few weeks I've also gained 6 lbs in weight. No this wasn't some chocolate binge or anything, it was no accident. It was a decision that i made so that I look a little healthier. My BMI went from 16.4 to 17.4 and I think it shows just a bit also. There is not much calorie different to maintain this weight, actually... anyway I'm still very young, I started CR way before almost everyone person on CRON out there. My body temperature hasn't changed, is still around 36.0 and I will hold this weight of 110-111 lbs now for a while. It was actually my weight last year, then I went back down to 105.

Unfortunately I am confused about my pre CRON heighest weight I achieved. I have some photographs and they indicate I might have at one point been heavier than I thought. The problem is I started to lose weight *years* before I even started CRON. I might be be 'CR'd' than I actually realize. Even my blood pressure on day 1 of CRON was 100/60. So I never experienced these massive changes like most older people.
I would love to have a physique like that of Bruce Lee. With my dedication I absolutely believe I could achieve it. Bruce lee at his lowest weight during his life was around 125 lbs! I think that was in way of the dragon or his last movie that never got finished. He went between 125-135 lbs... He was very toned, very little fat, and interestingly his diet was very good also. Vegetables, Fruits, smoothies, whey protein shakes... Maybe one day I can do this, but not yet, maybe by the time I am 35 we'll have a better idea on how far anti aging medicine has progressed so that I can make a better decision. Even at this time because of CRON I should be biologically younger anyway, not like your typical 35 year old.

part 2 coming tomorrow.

But you're so skinny!

This can come up a lot when the average westener confronts a serious CRONie. Girls tend to get away with it easier than guys, but not always. We're always seeing the media bash celebrities for being too skinny, then when they have their personal nutritionists and trainers get them in shape the media bash them for being too skinny. Then it's not always the media that are against it, even now the general public are unfortunately 'accepting' overweight as being normal. I don't just mean normal, I mean in recent years the average weight has gone up so much that our perception of what is a normal weight has completely changed. This is even backed up by some science that was reported over the last few years.

Now we have to be honest, serious anti aging kind of CR is for those that wish to take part in some experiment that we may never know the results. However, the whole country could use some CR right now. We should not expect everyone to jump onto CR and go into moderate to severe CR, but even milder reductions would signifiant improve health, work productivity, education, relationships and take a huge amount of strain off of free health services like the NHS here in the UK (which by the way I think do a brilliant job and i'm so greatful to have free health care in my country!) Diseases that are on the rise are perfectly preventable, such as heart disease, diabetes, stroke, and most cancers. Even other mild problems like common allergies such as hay fever can be reduced by a better diet. I used to have severe hay fever for 6 years, and since CR it's 99% better. The odd couple days in the summer I have symptoms but thats about it!

As readers come across my blog they might think this life style is 'extreme'. It can be, but it can also help you maintain a normal weight at the low end of normal and have a huge benefit of preventing diseases so that you're living most of your life disease free, much like those okinawans who were mildly calorie restricted for half their adult lives.

Since I began CR the issue of weight has come up over and over again. Questions are usually raised in the first few months of your weight where people around you need time to adjust to your new weight. There have been many reports among those on CR that during the early phase of weight loss people have made negative comments, and even when they're within a perfectly normal BMI. This comes back to how peoples perception of what is normal has changed.

If at some point the 'magic pill' comes along where it gives all the benefits of CR without actually doing serious CR then I would take it, and I would definitely gain about 10-15 pounds of weight back. I have always been lean all my life, ever since I was kid.

There is no denying that many of us on CR are freakishly skinny, and without proper care of nutrition, frequent lab work and other monitoring it can be a bit risky... if not done right you should consider quitting CR and just eating a healthy diet with increased calories.

Since the new research has come out theres been far more interest than usual in CR. We now have a wider age range in those that are on CRON. Many years ago people who were middle aged were typically the ones who started this kind of lifestyle. Now people like myself who are in their 20's are looking to push the limits of human longevity even more. In time we'll see if it was all worth it. I have placed my bets on that it will work, and it will work very well... especially for those that started from a young age.

Stay young forever

But don't you feel hungry?

You might have come across a lot of new articles recently and in many of them there are usually coments by the author or readers that calorie restriction is an awful way to live, you have constant hunger, you feel depressed and lack energy. Well for those of us that are on CR most of us can honestly say this is just not true. I will address some common questions but take one question at a time in each post because I am quite busy at the moment.

Do you always feel hungry on a CR diet - Since I started Calorie Restriction many years ago I designed a diet that worked for me. When I see people on 'diets' who consume bland salads it becomes obvious to me why they're hungry, and why they crave something more. Usually you'll find a typical person on a diet with a plate consisting of; A tomato or two, a small handful for iceburg lettuce, a white potato, maybe an egg some tuna, and usually a bad choice of salad dressing that is very high in fat like mayonnaise.
(picture taken in 2006)
I must say if I tried to live off this kind of salad I would have dropped CR a long time ago. However the fact is that when I consume food during my first few years of CR when I ate, I really ate a BIG meal... and it was usually much more than anyone else at the table. This photo to the left is a comparison picture to dinner that my mother cooked. My meal is the mountain of food you can see. On this I would put a good quality extra virgin olive oil, good balsamic vinegar, hot tomato salsa, and some herbs. Sometimes I just put tomato sauce which is low in sugar and salt on my veggies and it tastes fine. Plus it gives me much lycopene ^^

Now I eat more 'raw food' CR diet, where at least 70% of my diet consists of raw fruits and vegetables, and for what evidence shows that cooked is better I go with that. Although my meals are not of the size that I used to eat before, I am still well satisfied with what I eat. I hardly ever have any issues with hunger. Even now I still eat more food (but low in calories) than everyone else in my house (not put together of course) People often say to me "Don't you feel like you're missing out on these foods?". The short answer is NO. I could have the same meal every single day and enjoy it so much over and over again. Since I started on CR my diet and variety of foods that I eat has hugely increased, I no longer crave any sweets or processed foods (other than dark chocolate :D ). Every food I eat I make sure I absolutely enjoy it... everyone can make CRON an enjoyable experience if they design the best diet for them. Also when you're on CR your abilty to taste the foods you eat is far better, this is what I have experienced...

Thats all for today, more soon :-)

Carrots!

Just got my second harvest of carrots today and pulled up plenty! Can't wait to sow some more carrot seeds and this time have a far bigger area to grow them, and then store them to eat over a few months. I will update this post in the next couple days so check back for other information about the garden.







So far the easiest things to grow have been the cherry tomato plants and the carrots, hardly any real work needs to be done for them to grow other than watering, the strawberries are also now growing well but this year I don't expect a big harvest. I might let them spread in the garden box a bit. I expect I'll get around 30 strawbwerry plants next year which should be enough for me.

Although some things went good, somethings never really went that well, like the broccoli. The green caterpillars loved them and the plants just looked terrible recently so I pulled all but one of them. It's ok, I won't be doing so much broccoli next year because other plants you can get bigger harvests from in less time.


Please also take a moment to vote in my poll! Thanks :)

Canto and Owen [Rhesus Monkeys]

Below are some high resolution pictures of two rhesus monkeys around the same age, Owen is a couple years older than canto. Canto is 27 years of age right now and still looks like a youthful rhesus monkey. This is achieved by a reduction in calories alone.

I expect people who start CR at an early age, they could look extremely youthful in middle age and beyond.

People always think I am younger than my age -- usually people guess around 16-17 years old. I am actually only 3 months away from being 25!  I guess the difference can only grow over time. Is it possible to look only 25 at 50 years of age??? Maybe that might be pushing it, but it will be an interesting to see.


CLICK ON PICTURES FOR BETTER DETAIL

NORMAL DIET

CALORIE RESTRICTION DIET

Comments on the Rhesus Monkey study

CALORIE RESTRICTION REALLY DOES WORK IN MONKEYS

Over the past few days I've been looking around on the internet, checking out the CR Society email lists and the talk among the life extension community to see what others think of the study and whether or not this does really support calorie restriction working in non human primates and possibly humans. First lets look at the survival curve for overall mortality and non age related mortality. First if you haven't read the first post I did on this, scroll down to check it out first.

As you can see there is a big difference in survival in survival curve which excludes deaths from certain causes that are thought not to be caused by diseases and aging. Seven of the control Monkeys and Nine CR Monkeys died of non–age-related causes, which included complications of anesthesia, gastric bloat, endometriosis, and injury.

Anesthesia - The monkeys every year go through a cycle of tests, in order to perform some of these the monkeys have to be sedated. Sometimes even if the monkey was otherwise healthy, things can go wrong. The question is what has this got to do with aging, and should it be included when looking at the life extending effect of Calorie Restriction. Since the monkeys I believe are put under anesthesia quite frequently, possibly at least once a year (although I need to check on this to make sure) then there can be a risk when doing this. But if a monkey dies from anesthesia it tells us absolutely nothing about whether the animals aging was being slowed down or not by calorie restriction. Most humans do not go under anesthesia once or twice a year to have extensive medical tests done on them, in humans more care is probably taken as well in order not to kill the patient. If however there was a trend that as the monkeys aged they were more suceptible to death from anesthesia then I could understand including it in the age related mortality survival. Also taking into account any chronic diseases the subject might have had prior to going under anesthesia. The fact is these deaths could have been very well preventable. The researchers also never noted any increased risk of anesthesia deaths for the calorie restricted monkeys.

Injury - Accidents cannot be totally prevented. If someone fell and suffered severe head trauma, does this again tell you anything about whether or not calorie restriction has slowed down (or not) aging? Clearly the answer is no. One can possibly argue that the rhesus monkey might have been weak from aging and fell. But we don't know the details of how the injury occured, so we can only speculate. However the fact is accidents happen to 'anyone' and they do not tell you anything about aging other than when we see increase risk of falls from elderly humans which result in hip fracture and death. Should injuries be exlcuded? Absolutely! I have yet to see a good argument why they shouldn't.

Gastric bloat - I do not know how many monkey died from this but again this is a totally preventable death! From an article published in 2002 in the Wall Street Journal when refering the survival of the monkeys;

"Those figures exlcude monkeys whose deaths wree deemed accidental, such as when a batch of overcooked food caused a fatal stomach ailment called gastric bloat"

This is something that can happen at absolutely any age and should have been prevented, there is no reason at all to include it in the survival curve, and once again does not show whether or not CR was working. It was simply a preventable accident that can happen to any healthy monkey, both CR'd and Ad lib.

These are all deaths which I am very comfortable with the researchers excluding from their survival stats. They really do not tell us anything about aging and can happen at any age, and they were not increasing in frequency with age. In fact quite a few of the deaths seemed to be in the early stages of the study and later on the carers were better able to prevent more deaths from the causes above. In time I suspect that the overall mortality curve will show statistical significance. As there are three groups in the study we cannot tell what the average lifespan of the calorie restricted and ad lib groups are, but this data should be in quite soon. All animals are now apparently 27 years of age which is about the lifespan for a rhesus monkey, with the maximum being 40 years. So we could be waiting quite a while yet if a few of the monkeys reach 40 and beyond. So far almost all of the control monkeys have age related conditions that could eventually result in death, whereas in the CR animals a large percentage of them are in good health. As you can see below, througout the course of the study the control animals are experiencing more cancer, more cardiovascular disease, and big problems regulating glucose. Monkeys are particularly suceptible to age related diabetes than humans are, but calorie restriction seems to completely prevent this and even in two of the rhesus monkeys it reversed pre diabetes stage when they entered the study.

This tells us one important thing that all of us wish to have, a good quality of life. When on CR we are likely to spend more years with good health and then less time with ill health before death. It's not uncommon that people today spend decades with chronic health conditions that could be almost completely preventable. There has been some commentary about this study on the CR lists, this was one interesting point.

Michael Rae says; "This is the best of the 3 nonhuman primate studies, and still has some flaws: the actual differnce in Calorie intake has dwindled down to almost zero, because none of the animals are very engaged with their rather monotonous and restricted lives; the food isn't the best; there were definitely nutritional problems (such as excessive retinol, early on) in the diets; we don't *really* know how how to best care for and feed nonhuman primates, nor how long they can live in captivity, because so few have been studied; and above all, there's evidence that the AL group probably should've been restricted a bit more and the CRed animals restricted even further in turn (no effects on menstruation in the females, and probably some of the AL diabetes is related to modest overweight)."

Researchers are usually careful to make sure that the control group are normal weight and not affected by issues largely releated to being overweight. So animals are usually restricted by 20% from their true ad lib intake to avoid these complications. Michael is saying that the both groups should have been restricted more. I do believe the researchers found problems with restricting calories more severily in the CR group, they were deemed to be too thin and possibly pose future health problems which might cause issues further on in the study. I think the researchers were right to er on the side of caution here because the last thing we want is a complete failure because of health complications. There might have been none and most of the monkeys apparently were fine but like other studies in dogs, they increased the calories of some of the rhesus monkeys. I'm unsure if the information about there not being a difference between the both groups in terms of calorie intake, I heard this was an issue at the NIH study but not wisconsin. Maybe Michael has communicated with the researchers at Wisconsin or other people who knows about the situation there. And finally the food the monkeys are given, they are given monkey chow which is not the best food but it would be extremely difficult to give them anything else. With humans we can control our own diets, it's quite easy, and we know more in terms of what we need to stay healthy.

If anything the humans will respond even better. We have good access to health care (although the monkeys did recieve good health care also), we are not stuck in cages all our lives which would surely leave all of us quite depressed. The human data is pretty strong, even taken at face value and not comparing to the control groups, it's still very impressive. Almost every marker of health is improved by CR. Maybe now people should stop using the saying "It doesn't make you live longer, it just seems like it". Because this is not true :-)

Calorie Restriction is still the best way we can extend our lives, it's the best way to reach 100 and beyond, and it's the best way to ensure that you reach the point when medicine has advanced enough to slow and reverse aging.

If anyone has any good objections and why they should include the deaths I mention above, I'd love to hear it. So far there has been no good reasons why they have any indication or not whether CR is working.

EDITED: 13:30 15/07/2009 --

IN RESPONSE TO JUNK FOOD SCIENCE BLOG

Responding to some things from JunkFoodScience where I seen that there were many mistakes and misleading words.


Sandy Szwarc says;

"The non-aging-related causes of death included monkeys who died while taking blood samples under anesthesia, from injuries or from infections, such as gastritis and endometriosis."

The monkeys did not die from infections or gastritis. They mostly died for prentable causes and more care should have been taken i.e Not overcooking batch of food and killing the monkeys with gastric bloat. Anesthesia and injuries I already explained.

Sandy Szwarc says;

"As the supplemental data explains, 16 deaths from “non-age-associated causes were censored and their age of death used as the time variable in the regression"

She words it so the average reader without looking more into it would probably assume these 16 deaths or much more of them were all from the CR group. When is was 9 deaths for CR and 7 for ad lib.

Sandy Szwarc says

"but they could realistically be adverse effects of prolonged calorie restrictions on the animals’ health, their immune system, ability to handle stress, physical agility, cognition or behavior."

Well no there is no data that supports immune systems were weakened in monkeys and actually there is evidence monkeys have better immune systems under CR. They never died from infections in the study. The CR animals usually are able to withstand greater stress as seen in other lab animals, the CR monkeys were reported to be in better shape physically, as you can see by their posture and the way they move on videos. And in terms of cognition, it seems the CR monkeys are doing better from an earlier paper which showed better cognitive skills and problem solving. Not much behaviour differences were noted in the papers on the primates.

Then she makes this claim

"the control animals were overfed 20% more than their usual diet, while the CR monkeys’ diets were adjusted to keep them about 30% less than the control monkeys."

The control group were not as I recall fed 20% more than their ad lib intake, and they also had their food taken away from them also after the period of feeding time was over. She doesn't supply any references to support what shes saying. Then she assumes that the CR monkeys were fed 10% less to achieve a 30% reduction [after the 20% increase in control group] in calories? No, each CR monkey had its baseline intake calculated and reduced by 10% each month until reaching 30% below its normal calorie intake. The ad lib calorie intake was not increased by 20% to achieve this 30% reduction. The Ad lib monkeys were not true eat your brains out ad lib group, this was done at a previous study in Maryland where the control grop only reached 25 and CR group 32, but the ad lib intake in this study was also somewhat restricted to prevent obesity. Although it might have needed to be restricted a bit more and the CR group more also. All animals have a feeding period of about 8 hours, and food is removed from both groups and counted. So two differences in the Rhesus monkey studies. The NIA study reduced calorie intake from tables of how much each monkey should each should eat for their age and body weight, and the Wisconsin study reduced CR animals by 30% from their baseline intake after recording it for 3 - 6 months before starting the 10% reduction in calories every month for 3 months until reaching 30% restriction.

This presentation about the study shows that the female restricted group are now around 20% restricted comapred to the control group, whereas by their own baseline intake they at are 30% fewer calories. The males are able to stay around 30% restriction over time. This is the food intake for CR and Control group, they have their food measured everyday.



Some final thoughts

Now a suggestion to everyone. When reading blogs around the internet please try to be aware of false information, do a bit of research into it yourself. Many people have their own agenda usually don't actually read into the science properly, and they try to use clever words and twist stories around. Sometimes the mistake is genuine, but bottom line is look into yourself if you're not convinced. As for the JunkFoodScience blog, there were many obvious mistakes even after my first quick read through. Unfortunately for the average person reading they might easily be persuaded by people like her. My job here is to try and give you the latest information and media on CR, trying to be as honest as I can, and report the latest studies on health and try to give the correct data and not 'twist' stories around.

Thanks to a comment I recieved earlier you can read about Ms. Szwarc HERE . From looking at her funding sources, like McDonalds, she isn't exactly the kind of person you wan to listen to. She defends obesity, junk food, she claims obesity makes you healthier and a bunch of other crap. She is quite a good writer and can easily convince some people, don't be one of them. Also check another post about Szware HERE .

Whats going on the garden

Just a small garden update.

Broccoli plants - I had to pull two of the plants, the rest have held up well and the broccoli are growing well, albiet a small issue in one of the boxes which might be a boron deficiency. Though still perfectly edible broccoli. Here is the one I just harvested about 10 minutes ago. It came to around 450g but on here the scale must of went off.



Spinach - Well it all bolted and I pulled it up, I will put spinach back in after the fall and also MANY more carrots that I'm just about to sow tomorrow. Next time I defienitely need to start protecting my spianch better.

Cherry Tomatoes - I have totally lost count how many are growing, there are just so many flowers everywhere on the plants, all which will turn into lush small cherry tomatoes. I'm waiting for quite a lot to ripen at the moment but the plants are doing really well and producing a hell of a lot. Can't wait to harvest them, I'm gonna net them in the week too so I can stop them being eaten as they riepn. I must have hundreds growing at the moment. One mistake, I haven't really pruned the plants, I think I'm going to start that now. There is only one tomato plant that is not doing much, and that was the one which I put in the pot. I have now transplanted it into the big garden box.


Carrots - I pulled up a few carrots the other day and they were still a bit smaller than I expected, so I'll be leaving them for another 3 weeks. Though I ate what I harvetsed and they were nice. I just used them in a small salad I had.