Charlie Rose - Calorie Restriction

Jump to 4:35 to watch the part on the Calorie Restriction Rhesus Monkey study. The study started in 1989 and are now starting to show some big differences in health. The whole show can be seen on youtube just look for the 1st part and watch all of them.

Another use for Honey

I wrote a while ago that I use Manuka Honey because it's good for the throat to prevent infections, and it can be used topically too. Well now a new study shows that Honey is more effective than antibiotics at killing bacterial infections involved in chronic sinusitis. Many people in their lives get affected by sinusitis, whether it be an acute form or chronic. When it's chronic it can be a difficult thing to deal with and it seems like it never ends. Well luckily for me mine did and what cured it? A cold virus cured my bacterial sinusitis. That was kind of strange for me but the virus probably just got all the cells killed in the lining of the nose and the bacterial infection went out with the cells they so highly clung for a year :) No sinus problems since that 1 off thing I might add. I think it was actually caused by food being coughed up into sinuses at some point (broccoli). Weird hu?


So ok back to the story, in sciencedaily article it states;

Honey is very effective in killing bacteria in all its forms, especially the drug-resistant biofilms that make treating chronic rhinosinusitis difficult, according to research presented during the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in Chicago, IL.*

In eleven isolates of three separate biofilms (Pseudomonas aeruginosa, and methicicillin-resistant and -suseptible Staphylococcus aureus), honey was significantly more effective in killing both planktonic and biofilm-grown forms of the bacteria, compared with the rate of bactericide by antibiotics commonly used against the bacteria.

Source

One way to do this might be to dilute some Manuka honey (stronger than regular honey) and use with a neti pot or something to irrigate the sinuses. This could allow the honey to get to work in more areas of the sinus that trying to poke some thing up the nose and coating it that way. I wish I had known about this earlier, as it might have saved much trouble :)

Michael and Aprils CBS3 News Report (new)

Michael and April who most CRers in the CRS know did any interview back in 2007 and I put the video somewhere here on the blog, check through archives in last couple months. This video is slightly different and contains different parts of the interview not seen in previous news report

Okinawa's living relics

OKINAWA LIVING RELICS

The best video I've found on Okinawan longevity. This is a new one and I enjoyed it!

Excerpt from the documentary "How to live to 101".

A good part of the documentary on Okinawans and their longevity

Okinawa study has been going on for over 20 years now and they have the longest life expectancy in the world, and more centenarians than any other country. They have the lowest rates of almost all diseases of aging such as heart disease, cancer, dementia, diabetes, osteoporosis, they live healthy right up until they die, and the reasons for this are discussed in this short 8 minute video on living longer.

Some key points;

Eat fewer calories *
Eat vegetables, fruits, nuts, fish, and lean meats
Maintain a good social life and support
Practise something called "hara hachi bu" (eat only until 80% full)
Avoid or limit processed foods
Read "The Okinawa Program : How the World's Longest-Lived People Achieve Everlasting Health--And How You Can Too"

Doing the above might give you longer healthier life and maybe you could reach your 90's, 100, or become a super centenarian 110+ years.

Worlds oldest male 113

ARTICLE

Anyone measured his daily calorie intake yet??? :p

Seriously, the guys advice is to eat lots of vegetables, drink green tea, eat fish, drink milk, don't snack, don't smoke, and don't drink alcohol. Sounds like what a lot of us do on CRON now.

Here is a wiki article on the guy

This was him the other year in a picture. He said he wants to live forever... probably not likely, but I hope he has his wish to live at least another 10 years to beat Calments record of 122 years as the oldest person ever recorded.

longevity in response to treatment with serum collected from humans on calorie restricted diets

In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets.
Allard JS, Heilbronn LK, Smith C, Hunt ND, Ingram DK, Ravussin E; Pennington CALERIE Team, de Cabo R.

Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

Calorie restriction (CR) produces several health benefits and increases lifespan in many species. Studies suggest that alternate-day fasting (ADF) and exercise can also provide these benefits. Whether CR results in lifespan extension in humans is not known and a direct investigation is not feasible. However, phenotypes observed in CR animals when compared to ad libitum fed (AL) animals, including increased stress resistance and changes in protein expression, can be simulated in cells cultured with media supplemented with blood serum from CR and AL animals. Two pilot studies were undertaken to examine the effects of ADF and CR on indicators of health and longevity in humans. In this study, we used sera collected from those studies to culture human hepatoma cells and assessed the effects on growth, stress resistance and gene expression. Cells cultured in serum collected at the end of the dieting period were compared to cells cultured in serum collected at baseline (before the dieting period). Cells cultured in serum from ADF participants, showed a 20% increase in Sirt1 protein which correlated with reduced triglyceride levels. ADF serum also induced a 9% decrease in proliferation and a 25% increase in heat resistance. Cells cultured in serum from CR participants induced an increase in Sirt1 protein levels by 17% and a 30% increase in PGC-1alpha mRNA levels. This first in vitro study utilizing human serum to examine effects on markers of health and longevity in cultured cells resulted in increased stress resistance and an up-regulation of genes proposed to be indicators of increased longevity. The use of this in vitro technique may be helpful for predicting the potential of CR, ADF and other dietary manipulations to affect markers of longevity in humans.

Diet as of today

Heres just an example of what I eat in a day now. There are obviously some variations but they are small and the following is basically what I eat 95% of the time. Like sometimes I might have some strawberries, oranges, pineapples, Raisins among other things.


Breakfast

45g Oatmeal
Small Banana
Almonds
Walnuts
Blueberries
Whey Protein Drink
10g 70% Dark Chocolate
Essential Mix 3g
Cranberry Juice


Snack

Small apple
Bioactive Yogurt
cod liver oil
Essential Mix 3g (vitamins/minerals)


Dinner
Sweet potatoes
Extra Virgin Olive Oil
Broccoli steamed
Cauliflower steamed
Whey protein
Tomato sauce or salsa
Brussel sprouts steamed (not for a while they're not in stock!?)
1 clove of garlic

Later on I'll eat
sweet potato (the other half from earlier)
Red onions
Kale
Cherry tomatoes on the vine.
tsp of extra virgin olive oil
half a serving of whey protein
2 cloves of garlic

If I don't have the last bit of food I might just open up a low sugar/salt can of beans if I'm in a rush. I pretty much meet 100% of everything by the time I get to 1700-1800k/cal :)

Oh yes, I missed out the 5-10 cups of green tea I drink per day :D

Substance Found In Fruits And Vegetables Reduces Likelihood Of The Flu

News Article Sep. 3, 2008

Mice given quercetin, a naturally occurring substance found in fruits and vegetables, were less likely to contract the flu, according to a study published by The American Physiological Society. The study also found that stressful exercise increased the susceptibility of mice to the flu, but quercetin canceled out that negative effect.

Quercetin, a close chemical relative of resveratrol, is present in a variety of fruits and vegetables, including red onions, grapes, blueberries, tea, broccoli and red wine. It has been shown to have anti-viral properties in cell culture experiments and some animal studies, but none of these studies has looked specifically at the flu.

The researchers found that:

* Stressful exercise increased susceptibility to the flu. The mice that exercised to fatigue for three days were more likely to develop the flu than the mice that did not exercise (91% versus 63%).
* The mice that exercised developed the flu much sooner than those that did not (6.9 days versus 12.4 days).
* Mice that exercised and took quercetin had nearly the same rate of illness as those that did not exercise. In other words, quercetin canceled out the negative effect of stressful exercise.
* The severity of the symptoms among those mice that either did not exercise or those that exercised but took the quercetin was about the same.
* Quercetin had protective effects for the mice that did not exercise.


SOURCE: ScienceDaily

ill -- for 12 hours

I used the advice below and it seemed to work once again! I started to get a mild sore throat in work about 7pm last night, and by this morning I was 90% back to normal, and now at 6pm I feel about 95%. Isn't knowledge great! There are so many things one can do to abort these nasty viruses. I am in work all week so I took today off so that I can give my throat a rest as a precaution so I don't lose it (since I call people on the phone and need my voice!)

I heard that many CRers have less colds, and when they do have them they are gone in a very short amount of time. I remember Dean saying that he only usually gets colds now for half a day... pretty much what I experience.

Plans for the next year

I'm probably going to stop being lazy now and start doing a lot of different stuff. Back in November 2007 I mentioned that I would like to take Acting classes, so I been looking this up and found a few classes that start in end of September, might for those and they aint too expensive. Then I also got to take some singing lessons as in September I'm starting a new band. I also want to probably take a part time course at the college, maybe Spanish, but I'm not sure. I'd rather not waste an entire acedemic year doing nothing. I also am working much more now to so I can pay for all of this. This isn't all I want to do! I have so many ideas and plans, no wonder why I want to live a long time. I love everything haha :)

A few other things that I need to work on is doing Yoga more consistently again, and also want to get back into Karate as soon as possible too. But I won't push this because I need my achilles tendon to heal fully first.

As for the allergic reaction below, well, there was just some Rash that came up for no apparent reason other than some medicine I took last night for my stomach. It's pretty much 'almost' faded now, but I hope it goes by tomorrow because I have work! :D